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The Era of Genomics
1. In the spring of 2003, the complete sequencing of the human genome was announced, officially ushering in the genomic era. Today, gene expression profiles are being used to guide therapy and inform prognosis for a number of diseases; the use of genotyping is providing a new means to assess the risk of certain diseases as well as variation in response to a number of drugs; we are understanding better the role of certain genes in the causality of certain common conditions such as obesity and allergies. Despite these advances, we are still in the infancy of understanding and utilizing the complexities of genomics in the diagnosis, prevention, and treatment of disease.
2. Our task is still complicated nowadays by the fact that phenotypes are generally determined not by genes alone but by the interplay of genetic and environmental factors. Indeed, we have just begun to scratch the surface of possibilities that the era of genomics will provide to the practice of medicine.
3. The rapidity of these advances may seem overwhelming to the practicing physician. However, he or she has an important role to play in ensuring that these powerful technologies and sources of new information are applied with sensitivity and intelligence to the patient. Since genomics is such a rapidly evolving field, physicians and other health care professionals must continue to educate themselves so that they can apply this new knowledge to the benefit of their patients' health and well-being.
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What complicates the application of genomics nowadays?
It is connected with the fact that the complete sequencing of the human genome was announced only in the spring of 2003.
Being quite a new science, genomics requires absolutely new approaches to understanding peoples organisms’ potentialities.
Doctors are still in the infancy of understanding and utilizing the complexities of genomics in the diagnosis, prevention, and treatment of disease.
It is connected with the fact that phenotypes are generally determined not by genes alone but by the interplay of genetic and environmental factors.
