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Poliomyelitis
1. Poliomyelitis is an acute, viral, infectious disease spread from person to person, primarily via the fecal-oral route. The term means inflammation of the spinal cord’s grey matter, although a severe infection can extend into the brainstem and even higher structures, resulting in polioencephalitis, producing apnea that requires mechanical assistance such as an iron lung.
2. Although approximately 90% of polio infections cause no symptoms at all, affected individuals can exhibit a range of symptoms if the virus enters the blood stream. In about 1% of cases, the virus enters the central nervous system, preferentially infecting and destroying motor neurons, leading to muscle weakness and acute flaccid paralysis. Different types of paralysis may occur, depending on the nerves involved. Spinal polio is the most common form, characterized by asymmetric paralysis that most often involves the legs. Bulbar polio leads to weakness of muscles innervated by cranial nerves. Bulbospinal polio is a combination of bulbar and spinal paralysis.
3. Poliomyelitis was first recognized as a distinct condition by Jakob Heine in 1840. Its causative agent, poliovirus, was identified in 1908 by Karl Landsteiner. Although major polio epidemics were unknown before the late 19th century, polio was one of the most dreaded childhood diseases of the 20th century. Polio epidemics have crippled thousands of people, mostly young children; the disease has caused paralysis and death for much of human history. Polio had existed for thousands of years quietly as an endemic pathogen until the 1880s, when major epidemics began to occur in Europe; soon after, widespread epidemics appeared in the United States.
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Poliomyelitis is an acute, viral, infectious disease which affects the spinal cord’s grey matter resulting in dysfunction of the central nervous system leading to muscle weakness and different types of paralysis.
The term of «poliomyelitis» means inflammation of the spinal cord’s grey matter, although in a more severe form infection can extend into the brainstem and even higher structures leading to polioencephalitis.
Though the causative agent of poliomyelitis, poliovirus, was identified by Karl Landsteiner in 1908, a lot of children in Europe and in the United States suffered from this dreaded disease in the 20th century.
Poliomyelitis is an acute, viral, infectious disease being especially serious for children which is characterized by inflammation of the spinal cord’s grey matter caused by poliovirus identified in 1908 by Karl Landsteiner.